Publications

• Matsuo, E., Seki, H., Asai, T., Morimoto, T., Miyakawa, H., Ito, K., and Kamikouchi, A. Organization of projection neurons and local neurons of the primary auditory center in the fruit fly Drosophila melanogaster. J. Comp. Neurol. 524, 1099-1164, 2016.

• Miyazaki T, Lin TY, Ito K, Lee CH, Stopfer M. “A gustatory second-order neuron that connects sucrose-sensitive primary neurons and a distinct region of the gnathal ganglion in the Drosophila brain”. J Neurogenet. 29, 144-55, 2015

• Ito. K., Shinomiya, K., Ito, M., Armstrong, D., Boyan, G., Hartenstein, V., Harzsch, S., Heisenberg, M., Homberg, U., Jenett, A., Keshishian. H., Restifo, L., Rössler, W., Simpson, J., Strausfeld, N. J., Strauss, R., and Vosshall, L.B; The Insect Brain Name Working Group. A systematic nomenclature for the insect brain. Neuron, 81, 755-765, 2014.

• Otsuna, H., Shinomiya, K., and Ito.K. Parallel neural pathways in higher visual centers of the Drosophila brain that mediate wavelength-specific behavior. Front. Neural Circuits, 8, 8, 2014.

• Masuda-Nakagawa, L.M., Ito, K., Awasaki, T., O'Kane, C.J. A single GABAergic neuron mediates feedback of odor-evoked signals in the mushroom body of larval Drosophila. Front. Neural Circuits. 8, 35, 2014.

• Mu, L., Bacon, J.P., Ito, K., Strausfeld, N.J. Responses of Drosophila giant descending neurons to visual and mechanical stimuli. J Exp Biol. 217, 2121-2129, 2014.

• Flood, T., Iguchi, S., Gorczyca, M., White, B., Ito, K., and Yoshihara, M. A single pair of interneurons commands the Drosophila feeding motor program. Nature (Letter) 499, 83-87, 2013.

• Flood, T.F., Gorczyca, M., White, B.H., Ito, K., and Yoshihara, M. A large-scale behavioral screen to identify neurons controlling motor programs in the Drosophila brain. G3, 3, 1629-1637, 2013.

• Ito, M., Masuda, N., Shinomiya, K., Endo, K., and Ito, K. Systematic analysis of neural projections reveals clonal composition of the Drosophila brain. Curr. Biol, 23, 644–655, 2013.

• Ueno, T., Tomita, J., Tanimoto, H., Endo, K., Ito, K., Kume, S. and Kume, K. Identification of a dopamine pathway that regulates sleep and arousal in Drosophila. Nat Neurosci, 15, 1516-23, 2012.

• Aso, Y., Herb, A., Ogueta, M., Siwanowicz, I., Templier, T., Friedrich, A. B., Ito, K., Scholz, H. and Tanimoto, H. Three dopamine pathways induce aversive odor memories with different stability. PLoS genetics, 8: e1002768, 2012.

• Mu, L., Ito, K., Bacon, J. P. and Strausfeld, N. J. Optic glomeruli and their inputs in Drosophila share an organizational ground pattern with the antennal lobes. J Neurosci, 32: 6061-71, 2012.

• Endo, K., Karim, M. R., Taniguchi, H., Krejci, A., Kinameri, E., Siebert, M., Ito, K., Bray, S. J. and Moore, A. W. Chromatin modification of Notch targets in olfactory receptor neuron diversification, Nat Neurosci, 15: 224-233, 2012.

• Tanaka, N. K., Endo, K. and Ito, K. The organization of antennal lobe-associated neurons in the adult Drosophila melanogaster brain. J Comp Neurol, 520: 4067-4130, 2012.

• Shinomiya, K., Matsuda, K., Oishi, T., Otsuna, H., and Ito, K. Flybrain Neuron Database, a comprehensive database system of the Drosophila brain neurons. J Comp Neurol, 519, 807-833, 2011.

• Das, S., Sadanandappa, M. K., Dervan, A., Larkin, A., Lee, J. A., Sudhakaran, I. P., Priya, R., Heidari, R., Holohan, E. E., Pimentel, A., Gandhi, A., Ito, K., Sanyal, S., Wang, J. W., Rodrigues, V. and Ramaswami, M. Plasticity of local GABAergic interneurons drives olfactory habituation. Proc Natl Acad Sci U S A, 108: 646-54, 2011.

• Sejourne, J., Placais, P. Y., Aso, Y., Siwanowicz, I., Trannoy, S., Thoma, V., Tedjakumala, S. R., Rubin, G. M., Tchenio, P., Ito, K., Isabel, G., Tanimoto, H. and Preat, T. Mushroom body efferent neurons responsible for aversive olfactory memory retrieval in Drosophila. Nat Neurosci, 14, 903-10, 2011

• Larkin, A., Karak, S., Priya, R., Das, A., Ito, K., Rodrigues, V., and Ramaswami, M. Central synaptic mechanisms underlie short-term olfactory habituation in Drosophila larvae. Learn Mem, 17, 645-653, 2011.

• Miyazaki, T. and Ito, K. Neural architecture of the primary gustatory center of Drosophila melanogaster visualized with GAL4 and LexA enhancer-trap systems. J Comp Neurol, 518, 4147–4181, 2010.

• Ito, K. Organizational considerations for the steady development of digital brain atlases. Front Syst Neurosci, 4 (26), 2010.

• Aso, Y., Siwanowicz, I., Bracker, L., Ito, K., Kitamoto, T., and Tanimoto, H. Specific dopaminergic neurons for the formation of labile aversive memory. Curr Biol, 20, 1445-1451, 2010.

• Masuda-Nakagawa, L. M., Awasaki, T., Ito, K., and O'kane, C. J. Targeting expression to projection neurons that innervate specific mushroom body calyx and antennal lobe glomeruli in larval Drosophila. Gene Expr Patterns, 10, 328-337, 2010.

• Schnell, B., Joesch, M., Foerstner, F., Raghu, S. V., Otsuna, H., Ito, K., Borst, A., and Reiff, D. F. Processing of horizontal optic flow in three visual interneurons of the Drosophila Brain. J Neurophysiol, 103, 1646-57, 2010.

• Inagaki, H. K., Kamikouchi, A., and Ito, K. Methods for quantifying simple gravity sensing in Drosophila melanogaster. Nat Protoc, 5, 20-25, 2010.

• Inagaki, H. K., Kamikouchi, A., and Ito, K. Protocol for quantifying sound-sensing ability of Drosophila melanogaster. Nat Protoc, 5, 26-30, 2010.

• Tanaka, N. K., Ito, K. and Stopfer, M. Odor-evoked neural oscillations in Drosophila are mediated by widely branching interneurons. J Neurosci, 29, 8595-603, 2009

• Sakurai, M., Aoki, T., Yoshikawa, S., Santschi, L. A., Saito, H., Endo, K., Ishikawa, K., Kimura, K., Ito, K., Thomas, J. B., and Hama, C. Differentially expressed Drl and Drl-2 play opposing roles in Wnt5 signaling during Drosophila olfactory system development. J Neurosci, 29, 4972-4980, 2009

• Kamikouchi, A., Inagaki, H. K., Effertz, T., Fiala, A., Hendrich, O., Gopfert, M. C. and Ito, K. The neural basis of Drosophila gravity sensing and hearing. Nature (Article), 458, 165-171, 2009.

• Yorozu, S., Wong, A., Fischer, B. J., Dankert, H., Kernan, M. J., Kamikouchi, A., Ito, K., Anderson, D.J. Distinct sensory representations of wind and courtship song in the Drosophila brain. Nature (Letter), 458, 201-205, 2009.

• Okada, R., Awasaki, T. and Ito, K. GABA-mediated neural connections in the Drosophila antennal lobe. J Comp Neurol, 514, 74-91, 2009

• Busch, S., Selcho, M.., Ito, K. and Tanimoto, H. A map of octopaminergic neurons in the Drosophila brain and subesophageal ganglion. J Comp Neurol, 513, 643-667, 2009

• Kato, K., Awasaki, T. and Ito, K. Neuronal programmed cell death induces glial cell division in the adult Drosophila brain. Development, 136, 51-59, 2009.

• Tanaka, N. K., Tanimoto, H. and Ito, K. Neuronal assemblies of the Drosophila mushroom body. J Comp Neurol, 508, 711-755, 2008.

• Awasaki, T., Lai, S. L., Ito, K. and Lee, T. Organization and post-embryonic development of glial cells in the adult central brain of Drosophila. J Neurosci, 28, 13742-13753, 2008.

• Silbering, A. F., Okada, R., Ito, K. and Galizia, C. G. Odor information processing in the Drosophila antennal lobe: Anything goes? J Neurosci, 28, 13075-87, 2008.

• Das, A., Sen, S., Lichtneckert, R., Okada, R., Ito, K., Rodrigues, V. and Reichert, H. Drosophila olfactory local interneurons and projection neurons derive from a common neuroblast lineage specified by the empty spiracles gene. Neural Development, 3, 33, 2008.

• Lai, S. L., Awasaki, T., Ito, K. and Lee, T. Clonal analysis of Drosophila antennal lobe neurons: diverse neuronal architectures in the lateral neuroblast lineage. Development, 135, 2883-2893, 2008.

• Sachse, S., Rueckert, E., Keller, A., Okada, R., Tanaka, N. K., Ito, K. and Vosshal, L. B. Activity-dependent plasticity in an olfactory circuit. Neuron, 56, 838-50, 2007.

• Thum, A. S., Jenett, A., Ito, K., Heisenberg, M. and Tanimoto, H. Multiple memory traces for olfactory reward learning in Drosophila. J Neurosci, 27, 11132-8, 2007.

• Rister, J., Pauls, D., Schnell, B., Ting, C.-Y., Lee, C.-H., Sinakevitch, I., Morante, J., Strausfeld, N. J., Ito, K. and Heisenberg, M. Dissection of the peripheral motion channel in the visual system of Drosophila melanogaster. Neuron, 56, 155-170, 2007.

• Kamikouchi, A., Shimada, T. and Ito, K. Comprehensive classification of the auditory sensory projections in the brain of the fruit fly Drosophila melanogaster. J Comp Neurol, 499, 317-56. 2006.

• Otsuna, H. and Ito, K. Systematic analysis of the visual projection neurones of Drosophila melanogaster. I. Lobula-specific pathways. J Comp Neurol, 497, 928-58. 2006.

• Awasaki, T., Tatsumi, R., Takahashi, K., Arai, K., Nakanishi, Y., Ueda, R. and Ito, K. Essential role of the apoptotic cell engulfment genes draper and ced-6 in programmed axon pruning during Drosophila metamorphosis. Neuron, 50, 855-67. 2006.

• Liu, G., Seiler, H., Wen, A., Zars, T., Ito, K., Wolf, R., Heisenberg, M. and Liu, L. Distinct memory traces for two visual features in the Drosophila brain. Nature (Article), 439, 551-6. 2006.

• Akalal, D. B., Wilson, C. F., Zong, L., Tanaka, N. K., Ito, K. and Davis, R. L. Roles for Drosophila mushroom body neurones in olfactory learning and memory. Learn Mem, 13, 659-68. 2006.

• Marin, E. C., Watts, R. J., Tanaka, N. K., Ito, K. and Luo, L. Developmentally programmed remodeling of the Drosophila olfactory circuit. Development, 132, 725-37. 2005.

• Yoshida, S., Soustelle, L., Giangrande, A., Umetsu, D., Murakami, S., Yasugi, T., Awasaki, T., Ito, K., Sato, M. and Tabata, T. DPP signaling controls development of the lamina glia required for retinal axon targeting in the visual system of Drosophila. Development, 132, 4587-98. 2005.

• Awasaki, T. and Ito, K. Engulfing action of glial cells is required for programmed axon pruning during Drosophila metamorphosis. Curr Biol, 14, 668-677. 2004.

• Jefferis, G. S., Vyas, R. M., Berdnik, D., Ramaekers, A., Stocker, R. F., Tanaka, N. K., Ito, K. and Luo, L. Developmental origin of wiring specificity in the olfactory system of Drosophila. Development, 131, 117-130. 2004.

• Tanaka, N. K., Awasaki, T., Shimada, T. and Ito, K. Integration of chemosensory pathways in the Drosophila second-order olfactory centres. Curr Biol, 14, 449-57. 2004.

• Kido, A. and Ito, K. Mushroom bodies are not required for courtship behavior by normal and sexually mosaic Drosophila. J Neurobiol, 52, 302-11. 2002.

• Hayashi, S., Ito, K., Sado, Y., Taniguchi, M., Akimoto, A., Takeuchi, H., Aigaki, T., Matsuzaki, F., Nakagoshi, H., Tanimura, T., Ueda, R., Uemura, T., Yoshihara, M. and Goto, S. GETDB, a database compiling expression patterns and molecular locations of a collection of Gal4 enhancer traps. Genesis, 34, 58-61. 2002.

• Kurusu, M., Awasaki, T., Masuda-Nakagawa, L. M., Kawauchi, H., Ito, K. and Furukubo-Tokunaga, K. Embryonic and larval development of the Drosophila mushroom bodies: concentric layer subdivisions and the role of fasciclin II. Development, 129, 409-419. 2002.

• Verkhusha, V. V., Otsuna, H., Awasaki, T., Oda, H., Tsukita, S. and Ito, K. An enhanced mutant of red fluorescent protein DsRed for double labeling and developmental timer of neural fiber bundle formation. J Biol Chem, 276, 29621-29624. 2001.

• Yoshihara, M. and Ito, K. Improved Gal4 screening kit for large-scale generation of enhancer-trap strains. Dros Inform Service 83, 199-202. 2000.

• Awasaki, T., Saito, M., Sone, M., Suzuki, E., Sakai, R., Ito, K. and Hama, C. The Drosophila trio plays an essential role in patterning of axons by regulating their directional extension. Neuron, 26, 119-31. 2000.

• Ito, K., Suzuki, K., Estes, P., Ramaswami, M., Yamamoto, D. and Strausfeld, N. J. The organization of extrinsic neurones and their implications in the functional roles of the mushroom bodies in Drosophila melanogaster Meigen. Learn Mem, 5, 52-77. 1998.

• Ito, K., Awano, W., Suzuki, K., Hiromi, Y. and Yamamoto, D. The Drosophila mushroom body is a quadruple structure of clonal units each of which contains a virtually identical set of neurones and glial cells. Development, 124, 761-71. 1997.

• Ito, K., Sass, H., Urban, J., Hofbauer, A. and Schneuwly, S. GAL4-responsive UAS-tau as a tool for studying the anatomy and development of the Drosophila central nervous system. Cell Tissue Res, 290, 1-10. 1997.

• Ito, K., Urban, J. and Technau, G. M. Distribution, classification, and development of Drosophila glial cells in the late embryonic and early larval ventral nerve cord. Roux's Arch. Dev Biol, 204, 284-307. 1995.

• Halter, D. A., Urban, J., Rickert, C., Ner, S. S., Ito, K., Travers, A. A. and Technau, G. M. The homeobox gene repo is required for the differentiation and maintenance of glia function in the embryonic nervous system of Drosophila melanogaster. Development, 121, 317-332. 1995.

• Ito, K. and Hotta, Y. Proliferation pattern of postembryonic neuroblasts in the brain of Drosophila melanogaster. Dev Biol, 149, 134-148. 1992.

Reviews

• Awasaki, T., and Ito, K. Neurodevelopment: Regeneration switch is a gas. Nature 531, 182-183, 2016.

• Yoshihara, M. and Ito, K. Acute genetic manipulation of neuronal activity for the functional dissection of neural circuits-a dream come true for the pioneers of behavioral genetics. J Neurogenet, 26, 43-52, 2012.

• Ito, K. Organizational considerations for the steady development of digital brain atlases. Front Syst Neurosci, 4, 26, 2010.

• Ito, K. and Awasaki, T. Clonal unit architecture of the adult fly brain. in “Brain development in Drosophila melanogaster” pp.137-158, G. Technau ed. Landes Bioscience/Eureka, Austin, USA, 2008.

• Ito, K., Okada, R., Tanaka, N. K. and Awasaki, T. Cautionary observations on preparing and interpreting brain images using molecular biology-based staining techniques. Microsc Res Tech, 62, 170-86. 2003.

• Strausfeld, N. J., Hansen, L., Li, Y., Gomez, R. S. and Ito, K. Evolution, discovery, and interpretations of Arthropod mushroom bodies. Learn Mem, 5, 11-37. 1998.