Dr. Christoph Guschlbauer

• 2018-now: scientific assistant of Prof. Dr. Scott L. Hooper, having the status of a guest scientist at the University of Köln.
• 2009-2017 (with interruptions): Postdoctoral fellow in the Department of Animal Physiology with Prof. Dr. A. Büschges in the Institute of Zoology at the University of Köln.
• 2010, 2011: Postdoctoral fellow in the Department of Biological Sciences with Prof. Dr. S.L. Hooper at the Ohio University, Athens, USA.
• 2009: Dissertation (PhD) at the University of Köln.
• 2004-2009: Graduate student in the Department of Animal Physiology with Prof. Dr. A. Büschges in the Institute of Zoology at the University of Köln.
• 2002-2003: Diploma thesis in the Department of Animal Physiology with Prof. Dr. A. Büschges in the Institute of Zoology at the University of Köln.
• 1997-2002: Studies in Biology (Diploma) at the University of Köln.

Research

Most recently, my main focus lies on comparing the kinetics of different isometric muscle contractions and on investigating passive muscle and joint properties.

• Guschlbauer C*, Hooper SL*, Mantziaris C, Schwarz A, Szczecinski NS, Büschges A. (2022). Correlation between ranges of leg walking angles and passive rest angles among leg types in stick insects. Current Biology 2022 Apr 21: S0960-9822(22)00582-6. doi: 10.1016/j.cub.2022.04.013.
• Liessem S, Kowatschew D, Dippel S, Blanke A, Korsching S, Guschlbauer C, Hooper SL, Predel R, Büschges A (2021). Neuromodulation can be simple: myoinhibitory peptide, contained in dedicated regulatory pathways, is the only neurally-mediated peptide modulator of stick insect leg muscle. J Neurosci 41(13):2911–2929.
• von Twickel A*, Guschlbauer C*, Hooper SL, Büschges A (2019). Swing Velocity Profiles of Small Limbs Can Arise from Transient Passive Torques of the Antagonist Muscle Alone. Curr Biol. 29(1):1-12.e7
• Hosseinibarkooie S, Peters M, Torres-Benito L, Rastetter RH, Hupperich K, Hoffmann A, Mendoza-Ferreira N, Kaczmarek A, Janzen E, Milbradt J, Lamkemeyer T, Rigo F, Bennett CF, Guschlbauer C, Büschges A, Hammerschmidt M, Riessland M, Kye MJ, Clemen CS, Wirth B (2016). The Power of Human Protective Modifiers: PLS3 and CORO1C Unravel Impaired Endocytosis in Spinal Muscular Atrophy and Rescue SMA Phenotype. Am J Hum Genet. 99(3):647-665.
• Hooper SL, Thuma JB, Guschlbauer C, Schmidt J, Büschges A (2015). Cell dialysis by sharp electrodes can cause nonphysiological changes in neuron properties. J Neurophysiol. 114(2):1255-71.
• Knops S, Tóth TI, Guschlbauer C, Gruhn M, Daun-Gruhn S (2013). A neuromechanical model for the neuronal basis of curve walking in the stick insect. J Neurophysiol. 109(3):679-91.
• Blümel M, Guschlbauer C, Hooper SL, Büschges A. (2012) Using individual-muscle specific instead of across-muscle mean data halves muscle simulation error. Biol Cybern. 106(10):573-85.
• Blümel M, Guschlbauer C, Daun-Gruhn S, Hooper SL, Büschges A. (2012) Hill-type muscle model parameters determined from experiments on single muscles show large animal-to-animal variation. Biol Cybern. 106(10):559-71.
• Blümel M, Hooper SL, Guschlbauer C, White WE, Büschges A (2012). Determining all parameters necessary to build Hill-type muscle models from experiments on single muscles. Biol Cybern. 106(10):543-58.
• Hooper SL*, Guschlbauer C*, Blümel M, Rosenbaum P, Gruhn M, Akay T, Büschges A (2009). Neural control of unloaded leg posture and of leg swing in stick insect, cockroach, and mouse differs from that in larger animals. J Neurosci. 2009 Apr 1;29(13):4109-19. *contributed equally to the initiation of this work
• Hooper SL, Guschlbauer C, von Uckermann G, Büschges A (2007). Slow temporal filtering may largely explain the transformation of stick insect (Carausius morosus) extensor motor neuron activity into muscle movement. J Neurophysiol. 98(3):1718-32.
• Guschlbauer C, Scharstein H, Büschges A (2007). The extensor tibiae muscle of the stick insect: biomechanical properties of an insect walking leg muscle. J Exp Biol. 210(Pt 6):1092-108.
• Hooper SL, Guschlbauer C, von Uckermann G, Büschges A (2007). Different motor neuron spike patterns produce contractions with very similar rises in graded slow muscles. J Neurophysiol. 97(2):1428-44.
• Hooper SL, Guschlbauer C, von Uckermann G, Büschges A (2006). Natural neural output that produces highly variable locomotory movements. J Neurophysiol. 96(4):2072-88.

• Hooper SL, Guschlbauer C, Blümel M, von Twickel A, Hobbs KH, Thuma JB, Büschges A (2016). Muscles: Non-linear Transformers of Motor Neuron Activity. In: Prilutsky B, Edwards D (eds). Neuromechanical Modeling of Posture and Locomotion (pp. 163–194). Springer Series in Computational Neuroscience. Springer, New York, NY.