Dr. Christoph Guschlbauer

• 2009-2017 (with interruptions): Postdoctoral fellow in the Department of Animal Physiology with Prof. Dr. A. Büschges in the Institute of Zoology at the University of Köln.
• 2010, 2011: Postdoctoral fellow in the Department of Biological Sciences with Prof. Dr. S.L. Hooper at the Ohio University, Athens, USA.
• 2009: Dissertation (PhD) at the University of Köln.
• 2004-2009: Graduate student in the Department of Animal Physiology with Prof. Dr. A. Büschges in the Institute of Zoology at the University of Köln.
• 2002-2003: Diploma thesis in the Department of Animal Physiology with Prof. Dr. A. Büschges in the Institute of Zoology at the University of Köln.
• 1997-2002: Studies in Biology (Diploma) at the University of Köln.

Research

• Investigating a restorative preflex of a stick insect muscle opposing load increases in shortenings against loads less than muscle maximum steady state force (in collaboration with Prof. Dr. S.L. Hooper)
• Revealing joint rest angle differences after deflection of the ThC-, the CTr, and the FT-joints of all three legs in denervated stick insects (in collaboration with Dr. N.S. Szczecinski, M.Sc. C. Mantziaris, and M.Sc. Anna Schwarz)
• Comparing fast and slow locust muscle fiber responses to different motoneuronal activity levels (in collaboration with B.Sc. C. Klein and Prof. Dr. S.L. Hooper)

• Liessem S, Kowatschew D, Dippel S, Blanke A, Korsching S, Guschlbauer C, Hooper SL, Predel R, Büschges A (2021). Neuromodulation can be simple: myoinhibitory peptide, contained in dedicated regulatory pathways, is the only neurally-mediated peptide modulator of stick insect leg muscle. J Neurosci 41(13):2911–2929.
• von Twickel A*, Guschlbauer C*, Hooper SL, Büschges A (2019). Swing Velocity Profiles of Small Limbs Can Arise from Transient Passive Torques of the Antagonist Muscle Alone. Curr Biol. 29(1):1-12.e7
• Hosseinibarkooie S, Peters M, Torres-Benito L, Rastetter RH, Hupperich K, Hoffmann A, Mendoza-Ferreira N, Kaczmarek A, Janzen E, Milbradt J, Lamkemeyer T, Rigo F, Bennett CF, Guschlbauer C, Büschges A, Hammerschmidt M, Riessland M, Kye MJ, Clemen CS, Wirth B (2016). The Power of Human Protective Modifiers: PLS3 and CORO1C Unravel Impaired Endocytosis in Spinal Muscular Atrophy and Rescue SMA Phenotype. Am J Hum Genet. 99(3):647-665.
• Hooper SL, Thuma JB, Guschlbauer C, Schmidt J, Büschges A (2015). Cell dialysis by sharp electrodes can cause nonphysiological changes in neuron properties. J Neurophysiol. 114(2):1255-71.
• Knops S, Tóth TI, Guschlbauer C, Gruhn M, Daun-Gruhn S (2013). A neuromechanical model for the neuronal basis of curve walking in the stick insect. J Neurophysiol. 109(3):679-91.
• Blümel M, Guschlbauer C, Hooper SL, Büschges A. (2012) Using individual-muscle specific instead of across-muscle mean data halves muscle simulation error. Biol Cybern. 106(10):573-85.
• Blümel M, Guschlbauer C, Daun-Gruhn S, Hooper SL, Büschges A. (2012) Hill-type muscle model parameters determined from experiments on single muscles show large animal-to-animal variation. Biol Cybern. 106(10):559-71.
• Blümel M, Hooper SL, Guschlbauer C, White WE, Büschges A (2012). Determining all parameters necessary to build Hill-type muscle models from experiments on single muscles. Biol Cybern. 106(10):543-58.
• Hooper SL*, Guschlbauer C*, Blümel M, Rosenbaum P, Gruhn M, Akay T, Büschges A (2009). Neural control of unloaded leg posture and of leg swing in stick insect, cockroach, and mouse differs from that in larger animals. J Neurosci. 2009 Apr 1;29(13):4109-19. *contributed equally to the initiation of this work
• Hooper SL, Guschlbauer C, von Uckermann G, Büschges A (2007). Slow temporal filtering may largely explain the transformation of stick insect (Carausius morosus) extensor motor neuron activity into muscle movement. J Neurophysiol. 98(3):1718-32.
• Guschlbauer C, Scharstein H, Büschges A (2007). The extensor tibiae muscle of the stick insect: biomechanical properties of an insect walking leg muscle. J Exp Biol. 210(Pt 6):1092-108.
• Hooper SL, Guschlbauer C, von Uckermann G, Büschges A (2007). Different motor neuron spike patterns produce contractions with very similar rises in graded slow muscles. J Neurophysiol. 97(2):1428-44.
• Hooper SL, Guschlbauer C, von Uckermann G, Büschges A (2006). Natural neural output that produces highly variable locomotory movements. J Neurophysiol. 96(4):2072-88.

• Hooper SL, Guschlbauer C, Blümel M, von Twickel A, Hobbs KH, Thuma JB, Büschges A (2016). Muscles: Non-linear Transformers of Motor Neuron Activity. In: Prilutsky B, Edwards D (eds). Neuromechanical Modeling of Posture and Locomotion (pp. 163–194). Springer Series in Computational Neuroscience. Springer, New York, NY.